diff --git a/.lgtm.yml b/.lgtm.yml
new file mode 100644
index 00000000..8c185ef7
--- /dev/null
+++ b/.lgtm.yml
@@ -0,0 +1,17 @@
+---
+# This file contains configuration for the LGTM tool: https://lgtm.com/
+# The numcodecs repository is continuously scanned by the LGTM tool for
+# any security and/or code vulnerabilities. You can find the alerts here:
+# https://lgtm.com/projects/g/zarr-developers/numcodecs
+
+extraction:
+  python:
+    index:
+      exclude: cpuinfo.py
+
+path_classifiers:
+  test:
+    - numcodecs/tests
+
+queries:
+  - exclude: py/clear-text-logging-sensitive-data
diff --git a/docs/release.rst b/docs/release.rst
index 5650d3f1..c8662826 100644
--- a/docs/release.rst
+++ b/docs/release.rst
@@ -24,6 +24,9 @@ Maintenance
 * Remove trailing spaces and empty lines.
   By :user:`Dimitri Papadopoulos Orfanos <DimitriPapadopoulos>`, :issue:`341`.
 
+* Add LGTM.com configuration file
+  By :user:`Dimitri Papadopoulos Orfanos <DimitriPapadopoulos>`, :issue:`337`.
+
 .. _release_0.10.0:
 
 0.10.0